Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Medium or Average
Based on 15 Reviews
6.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Melatonin
10 mg
**
Top Medical Research Studies
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
Most Useful Reviews
9
Miracle sleep aid
3 people found this helpful
This Melatonin is miraculous! After a tough period of sleeplessness caused by strong drugs like vaben, this product allows me to fall asleep almost instantly and enjoy a full night’s sleep without addiction. My body has adjusted, enabling peaceful sleep even when I forget to take it.
Read More
8
Deep sleep achieved
3 people found this helpful
I can sleep well now. It works effectively without causing drowsiness or dullness upon waking. I'm glad I chose it based on others' reviews, as it surpasses the cheap 20mg I usually use.
Read More
7.5
Strong sleep onset
1 people found this helpful
I usually take "Natrol, Melatonin Advanced Sleep, Sustained Release, 10mg". This product works reasonably well for sleep onset, but I occasionally feel drowsy. I liked it enough to consider trying "Nature's Bounty, Melatonin".
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
- All Researches
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored REM sleep behavior disorder (RBD) as a complex condition that can be linked to a variety of underlying disorders. Through a literature review and insights from foundational texts, we recognized that RBD may emerge at any age and can initially appear as an isolated issue or be associated with other significant conditions like Parkinson’s and narcolepsy.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Read More
User Reviews
USERS' SCORE
Medium or Average
Based on 15 Reviews
6.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Miracle sleep aid
3 people found this helpful
This Melatonin is miraculous! After a tough period of sleeplessness caused by strong drugs like vaben, this product allows me to fall asleep almost instantly and enjoy a full night’s sleep without addiction. My body has adjusted, enabling peaceful sleep even when I forget to take it.
Read More
8
Deep sleep achieved
3 people found this helpful
I can sleep well now. It works effectively without causing drowsiness or dullness upon waking. I'm glad I chose it based on others' reviews, as it surpasses the cheap 20mg I usually use.
Read More
7.5
Strong sleep onset
1 people found this helpful
I usually take "Natrol, Melatonin Advanced Sleep, Sustained Release, 10mg". This product works reasonably well for sleep onset, but I occasionally feel drowsy. I liked it enough to consider trying "Nature's Bounty, Melatonin".
Read More
9
Sleep improvement
This sleep supplement really helps me to sleep!
Read More
9
Supports sleep
Helps me sleep well.
Read More
Frequently Asked Questions
9
Miracle sleep aid
3 people found this helpful
This Melatonin is miraculous! After a tough period of sleeplessness caused by strong drugs like vaben, this product allows me to fall asleep almost instantly and enjoy a full night’s sleep without addiction. My body has adjusted, enabling peaceful sleep even when I forget to take it.
6
Faster sleep
1 people found this helpful
After a long time struggling to sleep, I drank and was able to fall asleep quicker. When I close my eyes thinking about sleep apnea, I unexpectedly drift off.
4
Works initially
I’ve struggled with staying asleep for years; this melatonin provides the best relief I’ve found. After using it for four months, I noticed it becoming less effective, so I need to take a break to avoid dependency. I plan to use it again since it truly works.
2
Ineffective product
Honestly, there are better melatonins available. I have used this product multiple times, but it did not help with my sleep.
8
Deep sleep achieved
3 people found this helpful
I can sleep well now. It works effectively without causing drowsiness or dullness upon waking. I'm glad I chose it based on others' reviews, as it surpasses the cheap 20mg I usually use.
9
Supports sleep
Helps me sleep well.
0
Disappointing effects
This has been one of my most frustrating purchases! I bought it because my usual melatonin was out of stock, but it was a total disappointment. After four months of rigorous use, I felt no effects. It also caused stomach irritation and heartburn. I won't buy it again.
0
Mildly effective
It’s a mild hypnotic that gives normal sleep. However, if I use it and sleep, I experience a terrible headache the next day.
6
Quiet mind
For years, I struggled with sleeping problems and used sleeping pills. Now, I substitute with melatonin every other day. While it doesn't make me fall asleep immediately, it aids in settling my mind for sleep.
6
Helps sleep apnea
2 people found this helpful
Good for cheap. It helped me discontinue sleeping pills. Some individuals believe that melatonin may not be suitable for autoimmune diseases, but I experienced no issues while having Graves' disease. It appears more effective when taken alongside B vitamins.
5
Sleep onset support
4 people found this helpful
I'm expecting the effect recommended by my obstetrics and gynaecology teacher for treating sleep apnea. It makes me drowsy, aiding sleep onset, but I often wake up multiple times, suggesting it may not provide deep sleep. Should I consider another supplement?
2
Not effective
This melatonin did not improve my sleep nor my diet. I've opted for a different brand for treating my sleep apnea.
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
References
- Wei Z, Shen H, Wang F, Huang W, Li X, et al. Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients. Ann Med. 2024;56:2361825. 10.1080/07853890.2024.2361825
- Motlaq TM, Rahimi B, Amini S. Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial. J Pharm Health Care Sci. 2024;10:25. 10.1186/s40780-024-00347-9
- Dastan F, Gholizadeh Niari B, Adimi Naghan P, Barati S, Eskandari R. Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea. J Pharm Pharm Sci. 2023;25:418. 10.18433/jpps33252
- Schenck CH. REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications [Commentary]. Sleep Breath. 2022;26:1289. 10.1007/s11325-022-02574-6
